- Feb 06, 2018 -
Imidazole is a five-element aromatic heterocyclic compound containing two nitrogen atoms in the molecular structure, and the electron density of the 1-bit nitrogen atom in the imidazole ring is reduced, so that the hydrogen in the nitrogen atom is easy to leave by hydrogen ion. It is acidic and alkaline, and can form salt with strong alkali.
Physical properties: There is only imidazole derivative in nature, but no free imidazole.
Slightly soluble in benzene, petroleum ether, dissolved in ether, acetone, chloroform, pyridine, soluble in water (room temperature 70), ethanol. Significantly weak alkaline. Since the 1-bit-nh-bond and the 3-bit-n= bond form a hydrogen bond, the boiling point is higher, and when 1-bit hydrogen is replaced, hydrogen bonds cannot be formed and the boiling point drops. For heat stability, under 250 ℃ hardly decomposes (decomposition temperature 590 ℃). The reductant and oxidants are also stable, but they can form stable salts with inorganic acids. Some properties of aromatic family can be halogenated, nitrification, sulfonation and hydroxyl methylation under the action of Catalyst. And can be coupled with diazo salt in 2-bit.
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